Copper(II) gluconate CAS:527-09-3

  • Product Name:Copper(II) gluconate
  • CAS:527-09-3
  • Molecular formula:C12H22CuO14
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Copper(II) gluconate CAS:527-09-3

Copper(II) gluconate CAS:527-09-3 Basic information

Product Name: Copper(II) gluconate
Synonyms: Dapagliflozin Impurity 163;D-GLUCONIC ACID, COPPER(II) SALT;COPPER(II) GLUCONATE;COPPER(II) D-GLUCONATE;CUPRIC GLUCONATE;COPPER(+2)D-GLUCONATE;COPPER GLUCONATE;GLUCONIC ACID COPPER(II) SALT
CAS: 527-09-3
MF: C12H22CuO14
MW: 453.84
EINECS: 208-408-2
Product Categories: Organometallics;Biochemistry;Classes of Metal Compounds;Cu (Copper) Compounds;Glucose;Sugar Acids;Sugars;Transition Metal Compounds;Chemistry
Mol File: 527-09-3.mol

Copper(II) gluconate CAS:527-09-3 Chemical Properties

Melting point: 155-157 °C(lit.)
form: powder
Water Solubility: slightly soluble
refractive index: 16.5 ° (C=1, H2O)
Merck: 14,2640
CAS DataBase Reference: 527-09-3(CAS DataBase Reference)
EPA Substance Registry System: Copper gluconate (527-09-3)


 理化指标                              葡萄糖酸铜(C12H22CuO14),ω/%
浅蓝色细小粉末
Light blue fine powder
符合规定
Coincidence
Assay, ω/%                                                        98.0-102.0                                             99.82
还原性物质(以 D-C6H12O6 计),ω/%
Reducing substances, ω /%                               ≤1.0                                                     <1.0 氯化物(以 Cl 计),ω/%
Chloride, ω/%                                                    ≤0.07                                                   <0.07 硫酸盐(以 SO4 计),ω/%
Sulfate, ω/%                                                      ≤0.05                                                   <0.05 总砷(以 As 计)/(mg/kg)
Arsenic/(mg/kg)                                                ≤3.0                                                     <3.0 铅(Pb)/(mg/kg)
Lead/(mg/kg)                                                     ≤2.0                                                     <2.0

Copper(II) gluconate Usage And Synthesis
DescriptionCopper(II) gluconate is the copper salt of D-gluconic acid that is an organic acid. It can be used as a buffer for encapsulating some drugs into liposomes. Copper is an essential microelement for human beings and animals; it is needed to absorb ion from and gut and can help regulate blood pressure and heart rate. It is also a key component of multiple enzymes involved in many biochemical reactions. In this sense, the D-gluconic acid copper (II) salt can be used as a copper supplement to treat the copper deficiency induced anemia and nephrosis. It is also useful in the cancer chemotherapy being capable of enhancing the efficacy of the anticancer drug, disulfiram.
ReferencesDicko, Awa, et al. "Role of copper gluconate/triethanolamine in irinotecan encapsulation inside the liposomes." International Journal of Pharmaceutics 337.1(2007):219-228.
Ferris Iii, Frederick L, et al. "Nutritional supplement to treat macular degeneration.", EP1516542. 2009.
Georgewill Udeme Owunari, Siminialayi Iyeopu Minakiri. “Disulfiram and Copper gluconate in cancer chemotherapy: a review of the literature.” Cancer Research Journal 2.5(2014):88-92.
Chemical PropertiesCopper(II) gluconate, Cu(C6H11O7)2, is a light blue to blue-green, crystalline material that is soluble in water and slightly soluble in ethanol.
UsesSupplement (trace mineral).
Usescopper gluconate is cited as having skin-conditioning and skinprotecting functions.


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