2-Amino-1,3-propanediol CAS:534-03-2

  • Product Name:2-Amino-1,3-propanediol
  • CAS:534-03-2
  • Molecular formula:C3H9NO2
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2-Amino-1,3-propanediol CAS:534-03-2

2-Amino-1,3-propanediol CAS:534-03-2 Basic information

Product Name: 2-Amino-1,3-propanediol
Synonyms: 2-AMINO-1,3-PROPANDIOL;2-AMINO-1,3-PROPANEDIOL;2-Aminopropan-1,3-propanediol;2-Amino-1,3-dihydroxypropane;Serinol[2-Amino-1,3-Propandiol];S8002Dl-Serinol;2-Amino-1,3-Propanediol(Serinol);2-Amino-1,3-propanediol 99%
CAS: 534-03-2
MF: C3H9NO2
MW: 91.11
EINECS: 208-584-0
Product Categories: Pharmaceutical Intermediates;Alcohols and Derivatives;API intermediates;Intermediate
Mol File: 534-03-2.mol

2-Amino-1,3-propanediol CAS:534-03-2 Chemical Properties

density: 1.1278 (rough estimate)
Melting point: 52-55 °C(lit.)
Boiling point: 277 °C(lit.)
form: Adhering Crystalline Powder
Water Solubility: Soluble in water and alcohol.
refractive index: 1.4698 (estimate)
pka: 12.24±0.10(Predicted)
BRN: 635683
InChIKey: KJJPLEZQSCZCKE-UHFFFAOYSA-N
Fp: >230 °F
NIST Chemistry Reference: 2-Amino-1,3-propanediol(534-03-2)
Sensitive: Hygroscopic
CAS DataBase Reference: 534-03-2(CAS DataBase Reference)
EPA Substance Registry System: 1,3-Propanediol, 2-amino- (534-03-2)

Product Name

2-Amino-1,3-propanediol

CAS

534-03-2

MF

C3H9NO2

MW

91.11

Weight

100kg

Batch No


Items tested

Specifications

Results

Appearance

White or light yellow solid

pass

Purity %

99.0%

99.8%

Water %

0.5

0.30

Ethanolamine %

0.1

0.02







Conclusion

Conforms


2-Amino-1,3-propanediol Usage And Synthesis
Chemical Properties2-amino-1, 3-propanediol, which carries the trivial name of serinol, is an organic compound from the group of alkanolamines.The name serinol was chosen because of the structural similarity to the amino acidserine. In extension, derivatives thereof with substituents on the carbons of serinol are also called serinols.Under standard conditions, it is a solid, which is very soluble in water. 2-amino-1, 3-propanediol is a very stable, hygroscopic and corrosive substance.
Application
  • In biological field, the amino alcohol structure is widely found in many drugs especially antihistamines.

  • Serinol is used as an intermediate for non-ionic X-ray contrast agents like iopamidol (1-N,3-N-bi's (1,3-dihydroxypropan-2-yl) -5-[(2S) -2-hydroxypropanamido] -2,4,6-triiodobenzene-1,3-di-carboxamide, which is for example distributed as iopamiro®, isovue® (both Bracco Diagnostics Inc.) or scanlux® (Sanochemia). Iopamidol is employed as a contrast agent for angiography throughout the cardiovascular system.

  • Except the application in biochemical field, Serinol is used for the production of efficient anionic emulsifiers and nonionic polyethylene emulsions. It appears in personal care product formulations and show better base strength, lower neutral equivalent, and lower volatility than traditional amine emulsifiers.Furthermore, serinol constitutes a precursor for drugs dealing with pain treatment.

  • The difunctionality of serinol makes it useful as raw materials in polymer applications in both water- and solvent-based to increase the solubility of other components and improve solution stability. It functions as a pigment dispersion-aid dispersant to enhance the wetting and viscosity stability.

  • Serinol maintains a constant alkalinity in the boiling water flows and condensate not to form solid products which would impede line flow. It is applied for corrosion Inhibits. So it is widely employed in the preparation of water soluble cationic flocculants and ion exchange resins which adsorb solid and colloidal particles by electrostatic attraction. It is also used for water treatment, metal treatment and absorption of CO2 gas.


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