Ethambutol dihydrochloride CAS:1070-11-7

  • Product Name:Ethambutol dihydrochloride
  • CAS:1070-11-7
  • Molecular formula:C10H24N2O2.2ClH
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Ethambutol dihydrochloride CAS:1070-11-7

Ethambutol dihydrochloride CAS:1070-11-7 Basic information

Product Name: Ethambutol dihydrochloride
Synonyms: 1-Butanol, 2,2 -(ethylenediimino)di-, dihydrochloride, (+)- (8CI);d-2,2 -(Ethylenediimino)-di-1-butanol dihydrochloride;Ebutol;Etapiam;Ethambutold dihydrochloride;Etibi;Myambutol;Mycobutol
CAS: 1070-11-7
MF: C10H24N2O2.2ClH
MW: 277.23
EINECS: 213-970-7
Product Categories: Intermediates & Fine Chemicals;Pharmaceuticals;Peptide Synthesis/Antibiotics;Chiral Reagents;API;MYAMBUTOL
Mol File: 1070-11-7.mol

Ethambutol dihydrochloride CAS:1070-11-7 Chemical Properties

Melting point: 198-200°C
form: powder
storage temp.: Refrigerator
Water Solubility: Slightly soluble in water
solubility: H2O: soluble50mg/mL
Merck: 14,3720
PH: D25 +7.6° (c = 2 in water)
alpha: D25 +7.6° (c = 2 in water)
optical activity: [α]22/D 235°, c = 2 in 0.1 M HCl
Hydrolytic Sensitivity: (atm?m3/mol): 1.24 at 25 °C (approximate - calculated from water solubility and vapor pressure)
CAS DataBase Reference: 1070-11-7(CAS DataBase Reference)

执行标准

Standard adopted

USP40

分析项目

Items of analysis

质量标准

Specification

实测结果

Results

characteristics

A white,crystalline powder,freely soluble in water,soluble in alcohol,very slightly soluble in ether

A white, powder,freely soluble in water,soluble in alcohol,very slightly soluble in ether

identification

A: infrared absorption<197k> B:asolution (lin 10) responds to the tests for chloride <197>

A:positive B:positive

specific rotation

between 6.0° and 6.7°

6.5°

limit of aminovutanol

not more than 1.0%

1.0%

ordinary impurities

complies

complies

heavy metals

not more than 0.002%

0.002%

loss on drying

not more than 0.5%

0.06%

organic volatile impurities

meet the requirement

meets the requirements

assay

98.0%~100.5% C10H24N2O2·2HCL,calculates on the dried basis.

99.8%

结论

Conclusion

合格

Qualified


OriginatorMyambutol,Lederle,US,1967
UsesAntibacterial (tuberculostatic)
UsesAntituberculous


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