Kinetin CAS:525-79-1

  • Product Name:Kinetin
  • CAS:525-79-1
  • Molecular formula:C10H9N5O
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Kinetin CAS:525-79-1

Kinetin CAS:525-79-1 Basic information

Product Name: Kinetin
Synonyms: Kinetin, for plant cell culture, ≥99.0% (HPLC);cytokinin;cytokinin(askinetin);fap;kinetin(planthormone);n-(2-furanylmethyl)-1h-purin-6-amin;N6-FURFURYLADENINE;Adenine, N-furfuryl-
CAS: 525-79-1
MF: C10H9N5O
MW: 215.21
EINECS: 208-382-2
Product Categories: Purine;Amines;PLANT GROWTH REGULATOR;Biochemistry;Chemical Reagents for Pharmacology Research;Cytokinins;Nucleobases and their analogs;Nucleosides, Nucleotides & Related Reagents;Plant Growth Regulators;Inhibitors;Plant Hormones;Bases & Related Reagents;
Mol File: 525-79-1.mol

Kinetin CAS:525-79-1 Chemical Properties

density: 1.2639 (rough estimate)
Melting point: 269-271 °C (dec.)(lit.)
Boiling point: 355.49°C (rough estimate)
form: crystalline
storage temp.: −20°C
Water Solubility: Soluble in water (<1 mg/ml) at 25°C, Acetic acid (49.00-51.00 mg/ml), DMSO (43 mg/ml) at 25°C, ethanol (<1 mg/ml) at 25°C, 0.1 N Sodium hydroxide (1% w/v), methanol (slightly), and dilute aqueous hydrochloric acid or sodium hydroxide (freely).
refractive index: 1.7610 (estimate)
pka: pKa1 2.7; pKa2 9.9(at 25℃)
BRN: 21703
InChIKey: QANMHLXAZMSUEX-UHFFFAOYSA-N
Fp: 269-271°C
solubility: H2O: soluble
NIST Chemistry Reference: Kinetin(525-79-1)
Merck: 14,5311
CAS DataBase Reference: 525-79-1(CAS DataBase Reference)
EPA Substance Registry System: Kinetin (525-79-1)

TEST

SPECIFICATION

RESULTS

Appearance

White Crystals

Conform

Purity

≥99.0%

99.6%

Water Content

≤0.5%

0.32%

Heavy matal content

<20ppm

passed

Conclusion: Lot meets specification.

Kinetin Usage And Synthesis
DescriptionKinetin (or Vivakin) was introduced as Kinerase in the US as a new ingredient for the treatment of age related photodamage of skin. This 6- furfurylaminopurine is a synthetic cytokinin, a family of plant growth factors, and was shown to be a highly potent growth factor. In vitro, it was able to delay or prevent the onset of age-related changes in skin cells without affecting cellular lifespan. In a double-blind clinical trial, Kinetin (0.005%) partially reversed the clinical signs of photodamaged skin and demonstrated a good safety profile. It could have potential in psoriasis as well as in other proliferative skin disorders.
Chemical PropertiesWhite Solid
OriginatorSenetek (UK)
Usesauxin, plant growth regulator, plant cell division promotor
UsesPlant growth accelerator
UsesPlant growth regulator. To augment growth of microbial cultures: BE 632589 (1963 to Hoechst).
UsesA cell division factor found in various plant parts and in yeast. A plant growth regulator. Augments growth of microbial cultures
Brand nameKinerase
Synthesis Reference(s)The Journal of Organic Chemistry, 21, p. 1276, 1956 DOI: 10.1021/jo01117a016
Purification MethodsIt forms platelets from EtOH and sublimes at 220o, but is best done at lower temperatures in a good vacuum. It has been extracted from neutral aqueous solutions with Et2O. [Miller et al J Am Chem Soc 78 1375 1956, Bullock et al. J Am Chem Soc 78 3693 1956, Beilstein 26 III/IV 3586.]


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