Mepivacaine hydrochloride CAS:1722-62-9

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Mepivacaine hydrochloride CAS:1722-62-9

Mepivacaine hydrochloride CAS:1722-62-9 Basic information

Product Name: Mepivacaine hydrochloride
Synonyms: Mepivacaine Hydrochloride (200 mg);Ropivacaine base Mepivacaine HCL;(1-methyl-dl-piperidine-2-carboxylicacid)-2,6-dimethylanilidehydrochloride;1-methyl-2’,6’-pipecoloxylididehydrochloride;Mepivacaine HCl USP;2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)
CAS: 1722-62-9
MF: C15H22N2O.ClH
MW: 282.81
EINECS: 217-023-9
Product Categories: API;Sodium channel;Analgesic series;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File: 1722-62-9.mol

Mepivacaine hydrochloride CAS:1722-62-9 Chemical Properties

Melting point: 255-257°C (dec.)
form: powder
storage temp.: Refrigerator
color: white to beige
solubility: H2O: soluble20mg/mL, clear

Tests

 项目

Specifications  

标准

Results

结果

Description

性状

White or almost white crystalline powder

白色或类白色结晶性粉末

Complies

符合规定

Solubility

溶解度

Soluble in water and methanol,very slightly soluble in chloroform,practically insoluble in ether

在水和甲醇中易溶,在氯仿中微溶,在乙醚中几乎不溶。

Complies

符合规定

pH

about 5.0.

5.0

4.63

Identification

鉴别

A: By IR, To match with working standard

红外吸收图谱应与对照品一致

Complies

符合规定

B: Melting point(熔点):149°-153°

符合规定

C: A solution responds to the test for Chloride

氯化物鉴别应符合规定

Complies

符合规定

Loss on drying

干燥失重

≤1.0%

0.10%

Residue on ignition

炽灼残渣

≤0.1%

0.06%

Total impurity

总杂质

≤0.4%

0.012%

Residual  solvents

残留溶剂

Methanol

甲醇≤0.3%

Not detected

未检出

Ethanol

乙醇≤0.5%

Not detected

未检出

Glacial acetic acid

冰醋酸≤0.5%

Not detected

未检出

N-methylpyrrolidone

N-甲基吡咯烷酮≤0.053%

Not detected

未检出

Assay

含量

98.0%-102.0%

 (calculated on the dried basis以干品计)

99.33%

Conclusion 结论 : Conforms to USP41符合USP41标准


Mepivacaine hydrochloride Usage And Synthesis
Chemical PropertiesWhite Solid
Usesanesthetic (local)
UsesAn anti-inflammatory and analgesic


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