Minoxidil CAS 38304-91-5

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Minoxidil CAS 38304-91-5

Minoxidil CAS 38304-91-5 Basic information

Product Name: Minoxidil
Synonyms: 2,4-diamino-6-piperidinopyrimidine3-n-oxide;4-pyrimidinediamine,6-(1-piperidinyl)-3-oxide;6-amino-1,2-dihydro-1-hydroxy-2-imino-4-piperidinopyrimidine;6-piperidino-2,4-diaminopyrimidine3-oxide;alopexil;2,6-diamino-4-(piperidin-1-yl)pyrimidin-1-ium-1-olate
CAS: 38304-91-5
MF: C9H15N5O
MW: 209.25
EINECS: 253-874-2
Product Categories: Other APIs;ROGAINE;Heteroctcles;Bases & Related Reagents;Nitric Oxide Reagents;Nucleotides;Potassium channel;API;Intermediates & Fine Chemicals;Pharmaceuticals;API's
Mol File: 38304-91-5.mol

Minoxidil CAS 38304-91-5 Chemical Properties

density: 1.1651 (rough estimate)
Melting point: 272-274 °C (dec.)(lit.)
Boiling point: 348.61°C (rough estimate)
form: neat
storage temp.: Store at RT
Water Solubility: Soluble in water (2.2 mg/ml), 100% ethanol (29 mg/ml), propylene glycol, acetone, DMSO (6.5 mg/ml), and methanol.
refractive index: 1.7610 (estimate)
pka: 4.61(at 25℃)
solubility: Slightly soluble in water, soluble in methanol and in propylene glycol.
Merck: 14,6203

 名: 米诺地尔

Name Minoxidil

生产日期:

Date Of Produce20191213

批 号:

Batch No.CP04-191201

报告日期:

Date of Test: 20191226

检验依据:

Inspection basis : USP40

Items

Specifications

Results

性 状

Appearance

A white or almost white crystalline powder

almost white crystalline powder

 

溶解性

Solubility

Soluble in ethanol and propylene glycol, slightly soluble in methanol, water, almost insoluble in chloroform, acetone, ethyl acetate, n-hexane

Soluble in ethanol and propylene glycol, slightly soluble in methanol, water, almost insoluble in chloroform, acetone, ethyl acetate, n-hexane

鉴别

Identification

Infrared absorption spectrum consistent with the reference substance

complies

有机杂质

Organic impurities

≤1.5%

0.11%

干燥失重

Loss on drying

≤0.5%

0.2%

灼烧残渣

Residue on ignition

≤0.5%

0.2%

重金属

Heavy metals

≤20ppm

complies

含 量

Assay

97~103%

99.8%

有效期

Date of expiry

202211

结 论

CONCLUSION

 

Pass the USP40


UsesUsed as an antihypertensive and antialopecia agent. Minoxidil activates ATP-activated K+ channels
Usesantihypertensive, antialopecia agent
UsesA selective ATP dependent K+ (Kir6) channel activator


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