Albendazole S-oxide CAS 54029-12-8

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Albendazole S-oxide CAS 54029-12-8

Albendazole S-oxide CAS 54029-12-8 Basic information

Product Name: Albendazole S-oxide
Synonyms: Albendazole Sulphoxide HCL;methyl n-(6-propylsulfinyl-1h-benzoimidazol-2-yl)carbamate;Albendazole EP Impurity B-d7;Albendazole Impurity 2(Albendazole EP Impurity B);Methyl [5-(propylsulfinyl)-1Hbenzimidazol-2-yl]carbamate;Albendazole-EP-Imp-B;RS-8852;RIC
CAS: 54029-12-8
MF: C12H15N3O3S
MW: 281.33
EINECS: 628-805-8
Product Categories: Veterinary drugs;Inhibitors;Metabolites & Impurites;Animal Pharmaceuticals;Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites;Pharmaceuticals
Mol File: 54029-12-8.mol

Albendazole S-oxide CAS 54029-12-8 Chemical Properties

density: 1.40
Melting point: 226-228°C dec.
form: neat
storage temp.: -20°C Freezer
Water Solubility: 62mg/L(25 ºC)
color: colorless or white
pka: pKa 3.28±0.01(H2O t=25.0±0.1 I=0.1(NaCl))(Approximate); 9.93±0.01(H2O t=25.0±0.1 I=0.1(NaCl))(Approximate)
BRN: 677664

Product Name

Albendazole S-oxide

CAS

54029-12-8

Weight

500kgs

MF

C12H15N3O3S

Items tested

Specifications

Results

Appearance

White or almost white powder,

odorless

White or almost white powder,

odorless

Solubility

Very slightly soluble in ethanol, almost insoluble in acctone, insoluble in water, easily soluble in glacial acetic acid or sodium

hydroxide solution

Complies

Identification (IR)

Complies with spectrum of

Albendazole sulfoxide CRS

Complies

Identification (chemical)

Positive

Complies

Identification (HPLC)

The retained time of the principal obtained in the chromatogram of the test solution complies with the

standard solution

Complies

Absorption coefficient

542-576

558

Related substance

2.0%

0.6%

PH

5.5-7.0

6.0

Loss on drying

0.5%

0.2%

Sulphated ash

0.2%

0.1%

Fe

0.0030%

Complies

Assay

99%

(caculated on the dry basis)

99.1%

Conclusion

Conforms


Albendazole S-oxide Usage And Synthesis
Chemical PropertiesWhite to Off-White Powder
UsesA metabolite of Albendazole, an anthelmintic
UsesTubulin polymerization or assembled inhibitors


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