Atorvastatin calcium CAS 134523-03-8

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Atorvastatin calcium CAS 134523-03-8

Atorvastatin calcium CAS 134523-03-8 Basic information

Product Name: Atorvastatin calcium
Synonyms: LIPITOR;ATORVASTATIN CALCIUM SALT;ATORVASTATIN CALCIUM;ATORVASTATIN CA;[r-(r*, r*)]-7-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-4-(phenylaminocarbonyl)-1h-pyrrol-1-yl]-3,5-dihydroxy-heptanoic acid calcium salt;(3R,5R)-7-(2-(4-FLUOROPHENYL)-5-ISOPROPY
CAS: 134523-03-8
MF: C66H68CaF2N4O10
MW: 1155.36
EINECS: 200-659-6
Product Categories: Cardiovascular APIs;Pfizer compounds;Pharmaceutical intermediates;Isotope;LIPITOR;Aromatics;Chiral Reagents;Antilipemic agent;API;Atorvastatin;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Active Pharmaceutical Ingredients
Mol File: 134523-03-8.mol

Atorvastatin calcium CAS 134523-03-8 Chemical Properties

Melting point: 176-178°C
form: white powder
storage temp.: Store at +4°C
solubility: DMSO: ≥10mg/mL

Tested Items

Specifications

Results

Appearance

White or off white crystalline powder

White crystalline powder

PurityHPLC

99.0%

99.92%

Heavy metal

10

10

Specific optical rotation

-7.0~-9.0

-8.1

Water content%

3.5~5.5%

4.3%

Ca%

3.0-3.6%

3.5%

Single unknown impurities%

0.1%

0.08%

Total impurities

1.0%

0.08%

Conclusion

Positive


UsesA selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Usesantihyperlipidemic, HMGCoA reductase inhibitor
UsesDMSO and EtOH soluble
UsesThe primary uses of atorvastatin is for the treatment of dyslipidemia and the prevention of cardiovascular disease.
UsesA selective, competitive HMG-CoA reductase inhibitor. The only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia


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