Fenbendazole CAS:43210-67-9 Basic information
|Synonyms:||hoe881;Fenbedazole;5-(phenylthio)-2-benzimidazolecarbamic acid methyl ester;Methyl 5-phenylthio-1H-benaimidazol-2-yl carbamate;fenbendazol;Carbamic acid, 5-(phenylthio)-1H-benzimidazol-2-yl-, methyl ester;Febendazole;2-(Methoxycarbonylamino)-5-(phenylthio|
|Product Categories:||ProteasomeInhibitors;Amines;Veterinaries;Aromatics;Heterocycles;Sulfur & Selenium Compounds;PHARMACEUTICALS;Active Pharmaceutical Ingredients;API;Intermediates & Fine Chemicals;PANACUR;Other APIs;vermifuge|
Fenbendazole CAS:43210-67-9 Chemical Properties
Should be white or almost white powder
Almost white powder
Should be concordant 可 ith the RS spectrum
Concordant with the RS spectrum 与对照的红外光谱图对照一致
Any other impurity (biggest)
Loss on drying
Residue on ignition
The conclusion: This product conform the standard requirement of EP8 standard.
|Fenbendazole Usage And Synthesis|
|Benzimidazole anthelmintics||Fenbendazole is a benzimidazole anthelmintic with a broad spectrum,high efficiency and low toxicity ,in the structure,it has a strong affinity with the parasite tubulin ,by influencing cell transport and energy metabolism,it plays a role in preventing the polymerization of micro tubes, which ultimately destroys the integrity of parasite cells and energy transmission.|
Fenbendazole is used to drive and to kill the animal gastrointestinal parasites, it not only has a highly anthelmintic activity on animal gastrointestinal roundworms, hookworms, whipworms, some tapeworms and nematodes , but also has a preferred effect on the part of the bronchial tree and lung parasites (Aelurostrongylus abstrutus and lung fluke) .
|Aofendazuo||Aofendazuo is a benzimidazole anthelmintic, also known as the Austrian phenol metronidazole, oxfendazole, benzene etomidate sulfoxide, benzene sulfur oxygen imidazole ,it is the sulfoxide form of Fenbendazole , white or off-white powder at room temperature, slight special smell, it can damage the microtubules of the worms epithelial cells of the gastrointestinal tract, and inhibit the worms uptake of glucose from the intestine.|
Aofendazuo is used for the treatment and control of gastrointestinal adults and larvae, it has a good effect on the treatment of in vivo roundworms and lung worms in pigs and sheep , including Oster nematodes (Ostertagia), Haemonchus , Trichostrongylus, Nematodirus , Cooper nematode (Cooperia), capillary nematodes (Capillaria), toothed Oesophagostomum (Oesophagostomum), Chabertia, Trichuris nematodes form (Trichuris) and dictyocaulasis ( Dictyocaulus) and so on.
The above information is edited by the chemicalbook of Tian Ye.
|Chemical Properties||Gray light brown crystalline powder. Melting point 233 ℃ (decomposition). Soluble in dimethyl sulfoxide (DMSO), slightly soluble in common organic solvents, insoluble in water. Odorless, tasteless.|
|Uses||Anthelmintic. Broad-spectrum, high efficiency, low toxicity, antiparasitic. It has a strong killing effect on Roundworm, nematodes, tapeworms, cysticercosis , Fasciola and other parasites, not only killing worms, especially having a great effect on Transitional larvae ehich are hazardous to the liver, lungs and intestines .Fenbendazole is a benzimidazole anthelmintic, not only having a highly anthelmintic activity for gastrointestinal nematodes adults and larvae , but also having a good effect on dictyocaulasis, flukes and tapeworms, in addition,it has a strong killing eggs effect.|