5-Aminolevulinic acid methyl ester hydrochloride CAS:79416-27-6 Basic information
| Product Name: | 5-Aminolevulinic acid methyl ester hydrochloride |
|---|---|
| Synonyms: | 5-AMINOLEVULINIC ACID METHYL ESTER HYDROCHLORIDE;5-AMINO-4-OXOPENTANOIC ACID METHYL ESTER HYDROCHLORIDE;5-AMINO-4-OXO-N-VALERIC ACID METHYL ESTER HYDROCHLORIDE;ALA METHYL ESTER HYDROCHLORIDE;H-TIC(OTBU)-OH APTS;methyl 5-amino-4-oxovalerate hydrochloride;D |
| CAS: | 79416-27-6 |
| MF: | C6H12ClNO3 |
| MW: | 181.62 |
| EINECS: | 279-151-1 |
| Product Categories: | Fatty & Aliphatic Acids, Esters, Alcohols & Derivatives |
| Mol File: | 79416-27-6.mol |
5-Aminolevulinic acid methyl ester hydrochloride CAS:79416-27-6 Chemical Properties
| Melting point: | 119-121° |
|---|---|
| Water Solubility: | very faint turbidity |
| Sensitive: | Light Sensitive/Hygroscopic |
| CAS DataBase Reference: | 79416-27-6(CAS DataBase Reference) |
Item | Inspection Standard | Results |
Appearance | A white or off-white powder | White powder |
Melting point | ≥ 115.0℃ | 120.7 ~ 121.8℃ |
Heavy Metals(Pb) | ≤ 20ppm | <20ppm |
Residual solvents | Acetone ≤ 5000ppm | 522ppm |
Loss on Drying | ≤ 1.5% | 0.26% |
Residue on Ignition | ≤ 0.5% | 0.2% |
Assay | ≥ 98.0% | 99.26% |
Conclusion：This product by inspection accords with the standard Corporation | ||
| 5-Aminolevulinic acid methyl ester hydrochloride Usage And Synthesis |
| Chemical Properties | 5-Aminolevulinic acid methyl ester hydrochloride is white powder |
| Uses | 5-Aminolevulinic acid methyl ester hydrochloride is used in photodynamic therapy. |
| Definition | ChEBI: The hydrochloride salt of methyl 5-aminolevulinate. A prodrug, it is metabolised to protoporphyrin IX, a photosensitizer, and is used in the photodynamic treatment of non-melanoma skin cancer (including basal cell carcinoma). Topical application results in an accumulation of protoporphyrin IX in the skin lesions to which the cream has been applied. Subsequent illumination with red light results in the generation of toxic singlet oxygen that destroys cell membranes and thereby kills the tumour cells. |
| Brand name | Metvixia (PhotoCure, Norway). |
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