4-Aminoantipyrine CAS:83-07-8

  • Product Name:4-Aminoantipyrine
  • CAS:83-07-8
  • Molecular formula:C11H13N3O
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4-Aminoantipyrine CAS:83-07-8

4-Aminoantipyrine CAS:83-07-8 Basic information

Product Name: 4-Aminoantipyrine
Synonyms: Metamizole EP Impurity B;4-amino-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-Pyrazol-3-one;4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one;4-amino-2,3-dimethyl-1-phenyl-3-pyrazolin-5-on;4-Amminoantipirina;Aminoantipyrin;Aminoazophenazone;Aminoazophene
CAS: 83-07-8
MF: C11H13N3O
MW: 203.24
EINECS: 201-452-3
Product Categories: Drug bulk;Pyridines, Pyrimidines, Purines and Pteredines;Antibiotic Explorer;Heterocycles;Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;PYRAMIDON;Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chem
Mol File: 83-07-8.mol

4-Aminoantipyrine CAS:83-07-8 Chemical Properties

density: 0.8
Melting point: 105-110 °C(lit.)
Boiling point: 340 C
form: Powder or Crystals
storage temp.: Store at RT.
Water Solubility: ca. 500 g/L (20 ºC)
refractive index: 1.4930 (estimate)
pka: pK1: 4.94(+1) (25°C)
BRN: 181635
solubility: H2O: 0.1 g/mL, clear
NIST Chemistry Reference: Aminoantipyrene(83-07-8)
Merck: 14,591
Stability: Stable. May be light sensitive.
Odor: Odorless
CAS DataBase Reference: 83-07-8(CAS DataBase Reference)
EPA Substance Registry System: 4-Aminoantipyrene (83-07-8)

Product Name 产品名称

4-Aminoantipyrine

Batch No.批号

20200305

Quantity 数量

50KG

Test Item

Requirement

Test Result

1. Appearance 外观

yellowish to pale-yellow crystals powder

PASS

2. melting point

104-109

106.5-107.4

3.Assay 含量

≥98%

99.26%

CONCLUSION

QUALIFIED

4-Aminoantipyrine Usage And Synthesis
Chemical PropertiesAmber crystalline powder
Uses

4-Aminoantipyrine is a metabolite of aminopyrine, having both analgesic and anti-inflammatory properties.
Coupling Reagent for Trinder’s reagents in colorimetric hydrogen peroxide detectionassays
Forms highly stable dyes by coupling with Trinder’s reagents in presence of Peroxidase and H2O2. Therefore suitable for use in test strip and solution diagnostics.

UsesIndicator for trace phenol determinations in water.
UsesA reagent for glucose determination in the presence of peroxidase and phenol
DefinitionChEBI: A pyrazolone, a member of the class of pyrazoles that is antipyrine substituted at C-4 by an amino group. It is a metabolite of aminopyrine and of metamizole.
Purification MethodsIt crystallises from EtOH or EtOH/ether. [Beilstein 25 III/IV 3554.]


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